PIMA516457

NKG2D Monoclonal Antibody (1D11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516457-Each-of-1 In Stock ₹ 52,688.00

PIMA516457 - Each of 1

₹ 52,688.00

In Stock

Quantity

1

Base Price: ₹ 52,688.00

GST (18%): ₹ 9,483.84

Total Price: ₹ 62,171.84

Antigen

NKG2D

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P26718

Gene Symbols

Klrk1

Immunogen

NKL cells.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation

Clone

1D11

Conjugate

Unconjugated

Gene

Klrk1

Gene Alias

CD314; D12S2489E; D6H12S2489E; killer cell lectin like receptor K1; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K, member 1; KLR; Klrk1; natural killer cell group 2D; natural killer cell receptor; NK cell receptor D; NK lectin-like receptor; Nkg2d; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKLLR; Nkrp2; NKR-P2; NKR-P2, ortholog of human NKG2D

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

22914

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti Human CD314 antibody, clone 1D11 recognizes CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1)
  • CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells
  • Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation
  • NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function
  • The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain
  • The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.