PIMA516598

HLA-DR/DP/DQ Monoclonal Antibody (Bu26), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516598-Each-of-1 In Stock ₹ 43,743.50

PIMA516598 - Each of 1

₹ 43,743.50

In Stock

Quantity

1

Base Price: ₹ 43,743.50

GST (18%): ₹ 7,873.83

Total Price: ₹ 51,617.33

Antigen

HLA-DR/DP/DQ

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.

P01911, P01920, P04440

Gene Symbols

HLA-DPB1, HLA-DQB1, HLA-DRB1

Immunogen

The details of the immunogen for this antibody are not currently available.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry

Clone

Bu26

Conjugate

FITC

Gene

HLA-DQB1

Gene Alias

beta1 domain MHC class II HLA DPB; CELIAC1; class II HLA beta chain; Clone P2-beta-3; DLA class II histocompatibility antigen, DR-1 beta chain; DLA DRBB1 beta chain; DLA-DR beta; DLA-DRB1; DLA-DRBB1; DPB1; DR-16; DRB; DRB1; DRBB1; DRw10; DW2.2/DR2.2; FLJ75017; FLJ76359; HLA class II antigen; HLA class II histocompatibility antigen, DP beta 1 chain; HLA class II histocompatibility antigen, DP(W4) beta chain; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA class II histocompatibility antigen, DR-1 beta chain; HLA class II histocompatibility antigen, DRB1-15 beta chain; HLA class II histocompatibility antigen, DRB1-16 beta chain; HLA class II histocompatibility antigen, DRB1-3 chain; HLA DP14-beta chain; HLA-D; HLA-DP; HLA-DP histocompatibility type, beta-1 subunit; HLA-DP1B; HLA-DPB; HLA-DPB1; HLA-DQ; HLA-DQB; HLA-DQB1; HLA-DR; HLA-DR1B; HLA-DRB; HLA-DRB1; HLA-DRB2; human leucocyte antigen DRB1; IDDM1; integral membrane glycoprotein; LA-DRB; lymphocyte antigen; lymphocyte antigen DRB1; major histocompatibility complex class II antigen beta chain; major histocompatibility complex, class II, DP beta 1; major histocompatibility complex, class II, DQ beta 1; major histocompatibility complex, class II, DR beta 1; MHC Class 2; MHC class II; MHC class II antigen; MHC class II antigen beta chain; MHC class II antigen DP beta 1 chain; MHC class II antigen DPB1; MHC class II antigen DPbeta1; MHC class II antigen DQB1; MHC class II antigen DRB1*15; MHC class II antigen DRB1*16; MHC class II antigen DRB1*3; MHC class II antigen HLA-DQ-beta-1; MHC class II DLA DRB1 beta chain; MHC class II DLA-DRB; MHC class II DLA-DR-beta-1; MHC class II DQ beta chain; MHC class II DR beta 1; MHC class II HLA-DP-beta-1; MHC class II HLA-DQ beta glycoprotein; MHC class II HLA-DR beta 1 chain; MHC class II HLA-DRB1; MHC class II HLA-DR-beta cell surface glycoprotein; MHC class II HLA-DRw10-beta; MHC class2 antigen; MHC DLA-DR-beta-1 precursor; MHC DQ beta; MHC HLA DPB1; MHC HLA-D; MHC II HLA; SS1; XXbac-BPG161M6.1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3115, 3119, 3123

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa)
  • They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes
  • Three loci, DR, DQ and DP, encode the major expressed products of the human class II region
  • The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells
  • They therefore have a critical role in the initiation of the immune response
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.