HLA-DQ Monoclonal Antibody (CC158), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528484-Each-of-1 | In Stock | ₹ 67,061.50 |
PIMA528484 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,061.50
GST (18%): ₹ 12,071.07
Total Price: ₹ 79,132.57
Antigen
HLA-DQ
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
Q9TVC8
Gene Symbols
BOLA-DQA1, BOLA-DQA2, BOLA-DQA3, BOLA-DQA5, BOLA-DQB
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
282494, 282495, 282534, 282535, 282536
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
Applications
Flow Cytometry
Clone
CC158
Conjugate
PE
Gene
BOLA-DQB
Gene Alias
BoLA-DQA; BOLA-DQA1; BOLA-DQA2; BOLA-DQA2 protein; BOLA-DQA3; BOLA-DQA5; BOLA-DQB; CELIAC1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatability complex class II; major histocompatibility complex, class II, DQ alpha 1 precursor; major histocompatibility complex, class II, DQ alpha 2; major histocompatibility complex, class II, DQ alpha 5; major histocompatibility complex, class II, DQ alpha, type 1; major histocompatibility complex, class II, DQ alpha, type 3; major histocompatibility complex, class II, DQ beta; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II antigen precursor; MHC class II DQ beta chain; MHC class II DQA; MHC class II DQA precursor; MHC class II DQA1 precursor; MHC class II DQA2 (BoLA-DQA2); MHC class II DQA2 precursor; MHC class II DQB precursor; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; similar to MHC class II DQA2 (BoLA-DQA2); Unknown (protein for MGC:127488); Unknown (protein for MGC:137100)
Host Species
Mouse
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Bovine
Product Type
Antibody
Isotype
IgG2a
Related Products
Description
- Mouse anti Bovine MHC class II DQ antibody, clone CC158 recognizes Bovine MHC Class II DQ
- MHC Class II molecules are constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma
- Reconstitute with 1.0ml of distilled water
- HLA-DQ is one of the HLA (human leukocyte antigen) molecules belonging to class II of the major histocompatibility protein (MHC) surface proteins
- HLA-DQ and the other MHC class II molecules are heterodimeric proteins consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane
- They play a central role in the immune system by presenting peptides derived from extracellular proteins
- MHC Class II molecules are expressed in antigen-presenting cells (APC: B lymphocytes, dendritic cells, macrophages) and present peptides endocytosed, digested, and loaded onto the proteins prior to their migration to the cell surface
- Other human MHC class II molecules are HLA-DP, HLA-DM, HLA-DR, HLA-DOA, and HLA-DOB
- HLA-DQ displays significant variability, particularly in the beta subunit within the region that affects the peptides bound and presented by the protein
- Different classes of DQ based on similar beta subunits allow for the grouping of these variants into serotypes, which can often be recognized by antibodies raised against these subunits
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.