Transferrin Receptor Monoclonal Antibody (DF1513), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516645-Each-of-1 | In Stock | ₹ 50,240.50 |
PIMA516645 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,240.50
GST (18%): ₹ 9,043.29
Total Price: ₹ 59,283.79
Antigen
Transferrin Receptor
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
P02786
Gene Symbols
TFRC
Immunogen
KGI cell line
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Ferret, Human, Mustelid, Rhesus Monkey
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry
Clone
DF1513
Conjugate
PE
Gene
TFRC
Gene Alias
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
698146, 7037, 711568
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
Related Products
Description
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- Mouse anti Human CD71 antibody, clone DF1513 recognizes the human CD71 cell surface antigen, a approximately 190 kDa homodimeric glycoprotein expressed by proliferating cells
- Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
- Endosomal acidification leads to iron release
- The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
- Transferrin receptor is necessary for development of erythrocytes and the nervous system
- Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.