PIMA190784

Transferrin Receptor Monoclonal Antibody (MRC OX-26), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA190784-Each-of-1 In Stock ₹ 59,363.00

PIMA190784 - Each of 1

₹ 59,363.00

In Stock

Quantity

1

Base Price: ₹ 59,363.00

GST (18%): ₹ 10,685.34

Total Price: ₹ 70,048.34

Antigen

Transferrin Receptor

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q62351, Q99376

Gene Symbols

TFRC

Immunogen

PHA activated rat lymphocytes

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Western Blot

Clone

MRC OX-26

Conjugate

Unconjugated

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Mouse

Purification Method

IgG fraction

Regulatory Status

RUO

Gene ID (Entrez)

22042, 64678

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA1-90784 detects CD71 from rat samples
  • Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.