CD61 Monoclonal Antibody (HM beta 3.1), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516709-Each-of-1 | In Stock | ₹ 24,875.50 |
PIMA516709 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,875.50
GST (18%): ₹ 4,477.59
Total Price: ₹ 29,353.09
Antigen
CD61
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.
O54890
Gene Symbols
ITGB3
Immunogen
Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry
Clone
HM beta 3.1
Conjugate
PE
Gene
ITGB3
Gene Alias
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
Host Species
Armenian Hamster
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
16416, 29302
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Form
Lyophilized
Related Products
Description
- Reconstitute with 1 mL of distilled water
- After reconstitution, store product undiluted at 4oC in the dark
- For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
- CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets and their precursors
- CD61 antigen plays a role in platelet aggregation and also as a receptor for fibrinogen, fibronectin, von Willebrand factor and vitronectrin
- CD61 is a 105 kDa glycoprotein that associates with either the alpha 11b integrin (CD41) or the alpha V integrin (CD51) at the cell surface
- CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51
- CD61 is a receptor for fibrinogen, fibronectin, Von Willebrand Factor, vitronectin and thrombospondin
- The CD61 protein product is composed of an alpha chain and a beta chain
- A given chain may combine with multiple partners resulting in different integrins
- CD61 is found along with the alpha IIb chain in platelets
- Like other integrins, CD61 is known to participate in cell adhesion as well as cell-surface mediated signaling
- Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.