CaMKIV Monoclonal Antibody (8C5B8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517038-Each-of-1 | In Stock | ₹ 55,447.00 |
PIMA517038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,447.00
GST (18%): ₹ 9,980.46
Total Price: ₹ 65,427.46
Antigen
CaMKIV
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q16566
Gene Symbols
CAMK4
Immunogen
Purified recombinant fragment of human CAMK4 (amino acids: 35-292 ) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
8C5B8
Conjugate
Unconjugated
Gene
CAMK4
Gene Alias
A430110E23Rik; AI666733; brain Ca(2+)-calmodulin-dependent protein kinase type IV; brain Ca++-calmodulin-dependent protein kinase type IV; Ca2+/calmodulin-dependent protein kinase type IV/Gr; Calcium/calmoduli; calcium/calmodulin dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase IV L homeolog; calcium/calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain; Calmodulin-dependent protein kinase IV; calspermin; CAM kinase- GR; CAM kinase IV; CAM kinase-GR; CAMK; CaMK IV; camk4; camk4.L; camk4-A; CAMK-GR; CAMKIV; CaMKIV/Gr; Ccdpk; D18Bwg0362e; EC 2.7.11.17; KCC4; kinase CaMK4; OTTHUMP00000222818; RATCCDPK; xCaM; XELAEV_18008011mg
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
814
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17038 targets CAMK4 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples
- The MA5-17038 immunogen is purified recombinant fragment of human CAMK4 (amino acids: 35-292 ) expressed in E
- Coli
- MA5-17038 detects CAMK4 which has a predicted molecular weight of approximately 58kDa
- CAMK4 (CaMKIV) is a serine/threonine protein kinase that phosphoryates CREB, oncoprotein 18, and SRF
- It has limited tissue distribution, and has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells
- The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression
- CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees
- In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects
- In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT)
- CaMKIV is encoded, along with calspermin, by the CaMKIV gene
- It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin
- The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.