DLL4 Monoclonal Antibody (4A11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517068-Each-of-1 | In Stock | ₹ 49,795.50 |
PIMA517068 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,795.50
GST (18%): ₹ 8,963.19
Total Price: ₹ 58,758.69
Antigen
DLL4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q9NR61
Gene Symbols
Dll4
Immunogen
Purified recombinant fragment of human DLL4 expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1, IgG2b
Applications
ELISA, Flow Cytometry, Western Blot
Clone
4A11
Conjugate
Unconjugated
Gene
Dll4
Gene Alias
AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
54567
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17068 targets DLL4 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples
- This product is derived from clone #4A11F8 Mouse IgG2b and clone #4A11G2 Mouse IgG1 The MA5-17068 immunogen is purified recombinant fragment of human DLL4 expressed in E
- Coli
- MA5-17068 detects DLL4 which has a predicted molecular weight of approximately 74.6kDa
- Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1
- DLL4 is expressed in the vasculature and plays a critical role in vascular development
- It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network
- DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation
- This in turn leads to a decrease in tumor growth, with no apparent toxicity.