LRP5 Monoclonal Antibody (2B11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517113-Each-of-1 | In Stock | ₹ 49,439.50 |
PIMA517113 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
LRP5
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O75197
Gene Symbols
LRP5
Immunogen
Purified recombinant fragment of human LRP5 expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Flow Cytometry, Western Blot
Clone
2B11
Conjugate
Unconjugated
Gene
LRP5
Gene Alias
BMND1; EVR1; EVR4; HBM; HGNC:6697; LDL receptor related protein 5; low density lipoprotein receptor-related protein 5; low density lipoprotein receptor-related protein 7; low-density lipoprotein receptor-related protein 5; Low-density lipoprotein receptor-related protein 7; LR3; Lrp5; LRP-5; LRP7; LRP-7; mKIAA4142; OPPG; OPS; OPTA1; VBCH2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4041
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA5-17113 targets LRP5 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples
- The MA5-17113 immunogen is purified recombinant fragment of human LRP5 expressed in E
- Coli
- MA5-17113 detects LRP5 which has a predicted molecular weight of approximately 179kDa
- LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway
- Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos
- Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins
- Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.