CD45RB Monoclonal Antibody (16A), PE, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA517886-Each-of-1 | In Stock | ₹ 19,580.00 |
PIMA517886 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 19,580.00
GST (18%): ₹ 3,524.40
Total Price: ₹ 23,104.40
Antigen
CD45RB
Classification
Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene Accession No.
P06800
Gene Symbols
Ptprc
Immunogen
TH2 cell clones, final boost with TH2 clone D10 Fusion Partner: Ag8.653
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry
Clone
16A
Conjugate
PE
Gene
Ptprc
Gene Alias
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
Host Species
Rat
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
19264
Content And Storage
4° C, do not freeze
Form
Liquid
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Description
- CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein
- CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis
- CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains
- CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
- CD45RB is expressed in microglia and inflammatory cells
- In addition to involvement in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is involved in DNA fragmentation during apoptosis
- CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells.