PIMA517920

Transferrin Receptor Monoclonal Antibody (R17217.1.4), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517920-Each-of-1 In Stock ₹ 22,116.50

PIMA517920 - Each of 1

₹ 22,116.50

In Stock

Quantity

1

Base Price: ₹ 22,116.50

GST (18%): ₹ 3,980.97

Total Price: ₹ 26,097.47

Antigen

Transferrin Receptor

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

Q62351

Gene Symbols

TFRC

Immunogen

Mouse CD71

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

R17217.1.4

Conjugate

Biotin

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

22042

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.