PIMA517922

Transferrin Receptor Monoclonal Antibody (R17217.1.4), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA517922-Each-of-1 In Stock ₹ 50,329.50

PIMA517922 - Each of 1

₹ 50,329.50

In Stock

Quantity

1

Base Price: ₹ 50,329.50

GST (18%): ₹ 9,059.31

Total Price: ₹ 59,388.81

Antigen

Transferrin Receptor

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 4-5mg/mL BSA and 0.02% sodium azide

Gene Accession No.

Q62351

Gene Symbols

TFRC

Immunogen

Friend erythroleukemia 745.6 induced for 5 days in 1.5% dimethyl sulfoxide.

Quantity

300 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

R17217.1.4

Conjugate

FITC

Gene

TFRC

Gene Alias

2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

22042

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples
  • Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes
  • Endosomal acidification leads to iron release
  • The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system
  • Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.