PIMA518081
PKP2 Monoclonal Antibody (8H6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA518081-Each-of-1 | In Stock | ₹ 61,588.00 |
PIMA518081 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 61,588.00
GST (18%): ₹ 11,085.84
Total Price: ₹ 72,673.84
Antigen
PKP2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% sodium azide
Gene Accession No.
Q99959
Gene Symbols
PKP2
Immunogen
Recombinant fragment, corresponding to amino acids 1-350 of Human Plakophilin 2 fused to maltose binding protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
8H6
Conjugate
Unconjugated
Gene
PKP2
Gene Alias
1200008D14Rik; 1200012P04Rik; AA516617; ARVD9; PKP2; Pkp2l; plakophilin 2; plakophilin-2
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5318, 67451
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This target has a predicted molecular weight of 97 kDa
- Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments
- Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress)
- Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration
- Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart
- Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.