PIMA518129

CD177 Monoclonal Antibody (MEM-166), Alexa Fluor™ 647, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA518129-Each-of-1 In Stock ₹ 44,989.50

PIMA518129 - Each of 1

₹ 44,989.50

In Stock

Quantity

1

Base Price: ₹ 44,989.50

GST (18%): ₹ 8,098.11

Total Price: ₹ 53,087.61

Antigen

CD177

Classification

Monoclonal

Conjugate

Alexa Fluor 647

Gene

CD177

Gene Alias

1190003K14Rik; CD177; CD177 antigen; CD177 molecule; cell surface receptor; HNA2A; HNA-2a; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; Pdp3; Polycythemia rubra vera protein 1; PRV1; PRV-1; RGD1562941; UNQ595/PRO1181

Host Species

Mouse

Purification Method

Size-exclusion chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57126

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Form

Liquid

Applications

Flow Cytometry, Western Blot

Clone

MEM-166

Formulation

PBS with 0.2% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.

Q8N6Q3

Gene Symbols

CD177

Immunogen

Human granulocytes

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG1

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Description

  • CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils
  • Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application
  • Ligand of CD177 has been identified as CD31 (PECAM-1)
  • CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule
  • The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).