PIMA524592

VANGL1 Monoclonal Antibody (CL0241), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA524592-Each-of-1 In Stock ₹ 59,185.00

PIMA524592 - Each of 1

₹ 59,185.00

In Stock

Quantity

1

Base Price: ₹ 59,185.00

GST (18%): ₹ 10,653.30

Total Price: ₹ 69,838.30

Antigen

VANGL1

Classification

Monoclonal

Concentration

0.7 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q8TAA9

Gene Symbols

VANGL1

Immunogen

Recombinant protein corresponding to Human VANGL1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

CL0241

Conjugate

Unconjugated

Gene

VANGL1

Gene Alias

KAI1 COOH-terminal interacting tetraspanin; KAI1 C-terminal interacting tetraspanin; Kitenin; Loop-tail protein 2; loop-tail protein 2 homolog; LPP2; STB2; Stbm; STBM2; strabismus; strabismus 2; Van Gogh-like protein 1; vang, van gogh-like 1; VANGL planar cell polarity protein 1; Vangl1; vang-like 1 (van gogh, Drosophila); vang-like protein 1

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

81839

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Immunogen sequence: DTESTYSGYS YYSSHSKKSH RQGERTRERH KSPRNKDGRG SEKSVTIQPP TGEPLLGNDS TRTEEVQDDN WGETTTAITG TSEHSISQED IARISKDMED SVGLDCKRY Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%
  • Vang-like 1 protein is a novel human homologue of Drosophila Van Gogh/Strabismus
  • The Vang-like 1 gene consists of at least 7 exons, and encodes a protein with four transmembrane domains and the C-terminal Ser/Thr-X-Val motif
  • Studies shows that the expression of the protein is significantly up-regulated in gastric cancer cell lines MKN28, MKN74, pancreatic cancer cell lines BxPC-3, PSN-1 and Hs766T
  • The protein may serve as an effector mediating the intestinal trefoil factor (ITF) healing response of the intestinal mucosa
  • The protein also serves as a diagnostic marker for hepatocellular carcinoma as well as a potential molecular target for development of novel therapeutic drugs
  • The pathological role of the protein has been identified in neural tube defects (NTD)
  • Human Vang-like 1 gene maps to chromosome 1p11-p13.1.