Kindlin 2 Monoclonal Antibody (OTI14A11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524938-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA524938 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
Kindlin 2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q8CIB5, Q96AC1
Gene Symbols
FERMT2
Immunogen
Full-length protein expressed in 293T cell transfected with human FERMT2 expression vector
Quantity
100μL
Primary or Secondary
Primary
Target Species
Canine, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
OTI14A11
Conjugate
Unconjugated
Gene
FERMT2
Gene Alias
AA960555; EGK_18193; Fermitin family homolog 2; fermitin family homolog 2 (Drosophila); fermitin family member 2; fermt2; im:7145859; im:7145859 protein; KIND2; kindlin 2; kindlin-2; LOC616981 protein; MIG2; mig-2; mitogen inducible 2; mitogen inducible gene 2 protein; mitogen-inducible gene 2 protein; PH domain-containing family C member 1; pleckstrin homology domain containing, family C (with FERM domain) member 1; pleckstrin homology domain containing, family C member 1; pleckstrin homology domain-containing family C member 1; Plekhc1; UNC112; UNC112B
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10979, 218952, 289992, 490693
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself
- Binds to membranes enriched in phosphoinositides
- Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes
- Required for the assembly of focal adhesions
- Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation
- Recruits FBLIM1 to focal adhesions
- Plays a role in the TGFB1 and integrin signaling pathways
- Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling
- [UniProt]