XRCC4 Monoclonal Antibody (OTI4H9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524983-Each-of-1 | In Stock | ₹ 52,287.50 |
PIMA524983 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,287.50
GST (18%): ₹ 9,411.75
Total Price: ₹ 61,699.25
Antigen
XRCC4
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q13426, Q924T3
Gene Symbols
XRCC4
Immunogen
Full-length protein expressed in 293T cell transfected with human XRCC4 expression vector
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
OTI4H9
Conjugate
Unconjugated
Gene
XRCC4
Gene Alias
2310057B22Rik; AW413319; AW545101; DNA repair protein XRCC4; SSMED; X-ray repair complementing defective repair in Chinese hamster cells 4; X-ray repair cross complementing 4; X-ray repair cross complementing protein 4; X-ray repair cross-complementing protein 4; XRCC4
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
108138, 7518
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage
- These genes share sequence similarity with the yeast DNA repair protein Rad51
- XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends
- XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination
- Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation.