PIMA525519

DNAJB2 Monoclonal Antibody (OTI4D12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525519-Each-of-1 In Stock ₹ 52,198.50

PIMA525519 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

DNAJB2

Classification

Monoclonal

Concentration

0.53 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P25686

Gene Symbols

DNAJB2

Immunogen

Full length human recombinant protein of DNAJB2 produced in HEK293T cell

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

OTI4D12

Conjugate

Unconjugated

Gene

DNAJB2

Gene Alias

2700059H22Rik; CMT2T; DnaJ (Hsp40) homolog, subfamily B, member 10; DnaJ (Hsp40) homolog, subfamily B, member 2; DnaJ heat shock protein family (Hsp40) member B2; dnaJ homolog subfamily B member 10; DnaJ homolog subfamily B member 2; dnaJ protein homolog 1; Dnajb10; DNAJB2; DSMA5; Heat shock 40 kDa protein 3; heat shock protein J1; heat shock protein, DNAJ-like 1; heat shock protein, neuronal DNAJ-like 1; HSJ1; HSJ-1; HSPF3; mDj8

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3300

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions
  • The presence of the J domain defines a protein as a member of the DnaJ family
  • DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein
  • The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis
  • The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function
  • DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis
  • DnaJB2 (DnaJ homolog subfamily B member 2), also known as HSJ1 or HSPF3, is expressed almost exclusively in the brain, with the highest levels in the frontal cortex and hippocampus
  • Two isoforms are produced due to alternative splicing.