ERI1 Monoclonal Antibody (OTI1B3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA525827-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA525827 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
ERI1
Classification
Monoclonal
Concentration
1.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q5FVR4, Q8IV48
Gene Symbols
ERI1
Immunogen
Full length human recombinant protein of ERI1 produced in HEK293T cell
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI1B3
Conjugate
Unconjugated
Gene
ERI1
Gene Alias
3 ' exoribonuclease; 3' exoribonuclease; 3110010F15Rik; 3'-5' exonuclease ERI1; 3'-5' exoribonuclease 1; 3'EXO; 3'HEXO; enhanced RNAi protein 1; enhanced RNAi three prime mRNA exonuclease homolog 1; ERI1; eri-1; Eri-1 homolog; exoribonuclease 1; HEXO; histone mRNA 3' end-specific exonuclease; histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; protei; protein 3'hExo; RGD1308378; Thex1; three prime histone mRNA exonuclease 1; three prime mRNA exonuclease 1
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
361159, 90459
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication
- A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates
- Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi)
- Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure
- Able to bind other mRNAs
- Required for 5.8S rRNA 3'-end processing
- Also binds to 5.8s ribosomal RNA
- Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.