DIS3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA558723-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA558723 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
DIS3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DIS3
Gene Alias
2810028N01Rik; bA555G22.1; DIS3; DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; DIS3 mitotic control homolog; DIS3 mitotic control homolog (S. cerevisiae); dis3p; EXOSC11; exosome complex exonuclease RRP44; exosome component 11; KIAA1008; mitotic control protein dis3 homolog; protein DIS3 homolog; RGD1304646; Ribosomal RNA-processing protein 44; RP11-342J4.3; RRP44
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22894
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q9Y2L1
Gene Symbols
DIS3
Immunogen
Recombinant protein corresponding to Human DIS3
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: EAYILFVRKN AIVVLIPKYG LEGTVFFEEK DKPNPQLIYD DEIPSLKIED TVFHVFDKVK VKIMLDSSNL QHQKIRMSLV EPQIPGISIP TDTSN Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 87%
- The exosome is involved in a multitude of cellular RNA processing and degradation events
- DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species
- DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain
- It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, μgtimately, for proper mitotic progression
- Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.