PIMA525900

PSMB7 Monoclonal Antibody (OTI4G9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA525900-Each-of-1 In Stock ₹ 52,198.50

PIMA525900 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

PSMB7

Classification

Monoclonal

Concentration

0.59 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P70195, Q99436, Q9JHW0

Gene Symbols

Psmb7

Immunogen

Human recombinant protein fragment corresponding to amino acids 58-277 of PSMB7 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Western Blot

Clone

OTI4G9

Conjugate

Unconjugated

Gene

Psmb7

Gene Alias

AU020723; beta-type proteasome 7 subunit; EGK_07890; hypothetical protein LOC511207; macropain chain Z; MC14; Mmc14; Multicatalytic endopeptidase complex chain Z; proteasome (prosome, macropain) subunit, beta type 7; proteasome (prosome, macropain) subunit, beta type, 7; proteasome 20S subunit beta 7; proteasome beta 7 subunit; proteasome catalytic subunit 2; proteasome subunit alpha; proteasome subunit beta 7; proteasome subunit beta type-7; proteasome subunit beta type-7 proprotein; proteasome subunit Z; protein serine kinase c17; Psmb7; RP11-101K10.7; Z

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100686423, 19177, 5695, 85492

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure
  • The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
  • Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
  • An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
  • This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome
  • Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit
  • This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).