PIPA5118209

PSMD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118209-Each-of-1 In Stock ₹ 39,427.00

PIPA5118209 - Each of 1

₹ 39,427.00

In Stock

Quantity

1

Base Price: ₹ 39,427.00

GST (18%): ₹ 7,096.86

Total Price: ₹ 46,523.86

Antigen

PSMD2

Classification

Polyclonal

Formulation

PBS with 0.03% ProClin 300; pH 7

Gene Accession No.

Q13200

Gene Symbols

PSMD2

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human PSMD2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Gene

PSMD2

Gene Alias

26S proteasome non-ATPase regulatory subunit 2; 26S proteasome non-ATPase regulatory subunit 2-like protein; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; 55.11 protein; 9430095H01Rik; AA407121; F23F1.8; I79_017809; MGC14274; P97; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; proteasome 26S subunit, non-ATPase 2; protein 55.11; PSMD2; RPN1; S2; TEG-190; testis expressed gene 190; Tex190; TNFR-associated protein 2; TRAP2; Tumor necrosis factor type 1 receptor-associated protein 2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5708

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator
  • The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits
  • The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits
  • Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway
  • An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides
  • This gene encodes one of the non-ATPase subunits of the 19S regulator lid
  • In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor
  • A pseudogene has been identified on chromosome 1.