CDKL2 Monoclonal Antibody (OTI12C2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526746-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA526746 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
CDKL2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q92772
Gene Symbols
CDKL2
Immunogen
Human recombinant protein fragment corresponding to amino acids 291-493 of CDKL2 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI12C2
Conjugate
Unconjugated
Gene
CDKL2
Gene Alias
5330436L21Rik; AI505225; CDC2-related kinase; Cdkl2; cyclin dependent kinase like 2; cyclin-dependent kinase-like 2; cyclin-dependent kinase-like 2 (CDC2-related kinase); Kkiamre; Kkm; P56; p56 KKIAMRE protein kinase; protein kinase p56 KKIAMRE; serine/threonine protein kinase KKIAMRE; serine/threonine-protein kinase KKIAMRE; testicular tissue protein Li 35
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
8999
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2
- ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif
- The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE
- KKIAMRE is predominantly expressed in testis, kidney, brain and lung
- KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF
- However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.