PIPA578378

CDKN2C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578378-Each-of-1 In Stock ₹ 48,905.50

PIPA578378 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

CDKN2C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKN2C

Gene Alias

C77269; CDK6 inhibitor p18; Cdkn2c; CDKN6; cyclin dependent kinase inhibitor 2C; cyclin-dependent inhibitor; cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase 6 inhibitor p18; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); INK4c; p18; p18INK4c; p18-INK4c; p18-INK6

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1031, 12580, 54238

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1.33 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

P42773, Q60772

Gene Symbols

CDKN2C

Immunogen

Recombinant protein encompassing a sequence within the center region of human p18 INK4c. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: Neuro2A, Raw264.7, C2C12, NIH-3T3 Predicted Reactivity: Human (100%), Rat (88%), Rhesus Monkey (100%), Bovine (89%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors
  • This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression
  • Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function
  • Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis
  • Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.