PIMA526871
HSF2 Monoclonal Antibody (OTI2A7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA526871-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA526871 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
HSF2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q03933
Gene Symbols
HSF2
Immunogen
Human recombinant protein fragment corresponding to amino acids 74-324 of HSF2 produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI2A7
Conjugate
Unconjugated
Gene
HSF2
Gene Alias
AI661205; heat shock factor 2; heat shock factor protein 2; Heat shock transcription factor 2; HSF 2; Hsf2; HSTF 2; HSTF2; MGC117376; MGC156196; MGC75048
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3298
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Prokaryotic and eukaryotic cells respond to thermal and chemical stress by inducing a group of genes collectively designated heat shock genes
- In eukaryotes, this gene expression is regulated primarily at the transcription level
- Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation
- HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level
- HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation
- Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus
- HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer
- Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.