PIMA527030
TDG Monoclonal Antibody (OTI3C11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527030-Each-of-1 | In Stock | ₹ 52,198.50 |
PIMA527030 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,198.50
GST (18%): ₹ 9,395.73
Total Price: ₹ 61,594.23
Antigen
TDG
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q13569
Gene Symbols
TDG
Immunogen
Human recombinant protein fragment corresponding to amino acids 160-253 of TDG produced in E.coli
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
OTI3C11
Conjugate
Unconjugated
Gene
TDG
Gene Alias
C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Host Species
Mouse
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
6996
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family
- Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine
- With lower activity, this enzyme also removes thymine from C/T and T/T mispairings
- TDG can also remove uracil and 5-bromouracil from mispairings with guanine
- This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine
- This gene may have a pseudogene in the p arm of chromosome 12.