PIMA527202

TIMM8A Monoclonal Antibody (OTI5C8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527202-Each-of-1 In Stock ₹ 52,198.50

PIMA527202 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

TIMM8A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

O60220

Gene Symbols

TIMM8A

Immunogen

Full length human recombinant protein of TIMM8A produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI5C8

Conjugate

Unconjugated

Gene

TIMM8A

Gene Alias

DDP; Ddp1; deafness dystonia protein 1; Deafness dystonia protein 1 homolog; deafness/dystonia peptide; DFN1; DXHXS1274E; Fci-12; Mitochondrial import inner membrane translocase subunit Tim8 A; MTS; TIM8; Tim8a; Timm8a; Timm8a1; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog A (yeast); translocase of inner mitochondrial membrane 8 homolog a1; translocase of inner mitochondrial membrane 8 homolog A1 (yeast); translocase of inner mitochondrial membrane 8A1; X-linked deafness dystonia protein

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1678

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane
  • Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane
  • Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space
  • The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins
  • Probably necessary for normal neurologic development.