PIMA527266

SLC22A17 Monoclonal Antibody (OTI2D6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527266-Each-of-1 In Stock ₹ 52,198.50

PIMA527266 - Each of 1

₹ 52,198.50

In Stock

Quantity

1

Base Price: ₹ 52,198.50

GST (18%): ₹ 9,395.73

Total Price: ₹ 61,594.23

Antigen

SLC22A17

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8WUG5

Gene Symbols

SLC22A17

Immunogen

Human recombinant protein fragment corresponding to amino acids 241-300 of SLC22A17 produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI2D6

Conjugate

Unconjugated

Gene

SLC22A17

Gene Alias

1700094C23Rik; 24p3 receptor; 24p3R; AU041908; AW555662; BOCT; Boit; brain-specific organic ion transporter; brain-type organic cation transporter; hBOIT; Lipocalin-2 receptor; mBOCT; Neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NgalR; NGALR2; NGALR3; organic cation transporter BOCT; potent brain type organic ion transporter; rBOCT; SLC22A17; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17; solute carrier family 22, member 17

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51310

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • The Slc22 family of organic anion and cation transporters (OATs, OCTs, OCTNs) are transmembrane proteins expressed predominantly in kidney and liver
  • Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2
  • Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2)
  • Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart
  • Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion
  • Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.