PIMA528616
RRAS2 Monoclonal Antibody (EM-50), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528616-Each-of-1 | In Stock | ₹ 25,053.50 |
PIMA528616 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,053.50
GST (18%): ₹ 4,509.63
Total Price: ₹ 29,563.13
Antigen
RRAS2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 15mM sodium azide; pH 7.4
Gene Accession No.
P62070
Gene Symbols
RRAS2
Immunogen
Human TC21
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
EM-50
Conjugate
Unconjugated
Gene
RRAS2
Gene Alias
2610016H24Rik; C86394; Ras-like protein TC21; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; Rras2; TC21; Teratocarcinoma oncogene
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
22800
Content And Storage
4° C, do not freeze
Form
Liquid
Related Products
Description
- The mouse monoclonal antibody EM-50 recognizes R-Ras2 / TC21 protein and does not react with R-Ras1, H-Ras, K-Ras, and N-Ras
- RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers
- The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%
- RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases
- It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins
- RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.