BLNK Recombinant Rabbit Monoclonal Antibody (125), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530089-Each-of-1 | In Stock | ₹ 41,385.00 |
PIMA530089 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,385.00
GST (18%): ₹ 7,449.30
Total Price: ₹ 48,834.30
Antigen
BLNK
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q8WV28
Gene Symbols
BLNK
Immunogen
Recombinant Human BLNK/Ly-57/SLP-65 protein (Met1-Ser456)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA
Clone
125
Conjugate
Unconjugated
Gene
BLNK
Gene Alias
AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
29760
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This antibody has specificity for Human BLNK/Ly-57/SLP-65
- B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans
- It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa)
- It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk
- Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.