PIMA527007

BLNK Monoclonal Antibody (OTI4C9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527007-Each-of-1 In Stock ₹ 52,287.50

PIMA527007 - Each of 1

₹ 52,287.50

In Stock

Quantity

1

Base Price: ₹ 52,287.50

GST (18%): ₹ 9,411.75

Total Price: ₹ 61,699.25

Antigen

BLNK

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8WV28

Gene Symbols

BLNK

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-292 of BLNK produced in E.coli

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

OTI4C9

Conjugate

Unconjugated

Gene

BLNK

Gene Alias

AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa

Host Species

Mouse

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29760

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans
  • It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa)
  • It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk
  • Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.