PIMA530339
DLL4 Monoclonal Antibody (15), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530339-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA530339 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
DLL4
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
Q9NR61
Gene Symbols
Dll4
Immunogen
Recombinant Human DLL4/Delta-like 4 protein (Met1-Pro524)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA
Clone
15
Conjugate
Unconjugated
Gene
Dll4
Gene Alias
AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
54567
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human DLL4/Delta-like 4
- Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1
- DLL4 is expressed in the vasculature and plays a critical role in vascular development
- It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network
- DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation
- This in turn leads to a decrease in tumor growth, with no apparent toxicity.