DLL4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA523453-Each-of-1 | In Stock | ₹ 44,277.50 |
PIPA523453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.50
GST (18%): ₹ 7,969.95
Total Price: ₹ 52,247.45
Antigen
DLL4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Dll4
Gene Alias
AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
54485, 54567
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA and 0.05% sodium azide
Gene Accession No.
Q9JI71, Q9NR61
Gene Symbols
Dll4
Immunogen
Partial synthetic peptide between amino acids 550-610 of human DLL4.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1
- DLL4 is expressed in the vasculature and plays a critical role in vascular development
- It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network
- DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation
- This in turn leads to a decrease in tumor growth, with no apparent toxicity.