PIMA530638
LDLR Monoclonal Antibody (12), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA530638-Each-of-1 | In Stock | ₹ 32,485.00 |
PIMA530638 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 32,485.00
GST (18%): ₹ 5,847.30
Total Price: ₹ 38,332.30
Antigen
LDLR
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P01130
Gene Symbols
LDLR
Immunogen
Recombinant Human LDLR/LDL R/LDL Receptor Protein (Met1-Arg788)
Quantity
100μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Applications
ELISA
Clone
12
Conjugate
Unconjugated
Gene
LDLR
Gene Alias
FH; FHC; Hlb301; I79_005860; LDL receptor; LDLA; LDLCQ2; LDLR; ldl-r; LDLRA; low density lipoprotein receptor; low density lipoprotein receptor protein; low-density lipoprotein receptor; low-density lipoprotein receptor class A domain-containing protein 3
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
3949
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This product is preservative free
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
- This antibody has specificity for Human LDLR/LDL R/LDL Receptor
- The low density lipoprotein receptor (LDL-R) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands
- Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis
- At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place
- Mutations in the LDL-R gene cause the autosomal dominant disorder, familial hypercholesterolemia
- Along with SCARB1, CLDN1, and the tetraspanin superfamily member CD81, LDL-R has been reported to be an entry factor for the Hepatitis C virus
- At least three isoforms of LDL-R are known to exist.