PIMA530680

IL-29 Monoclonal Antibody (03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA530680-Each-of-1 In Stock ₹ 32,485.00

PIMA530680 - Each of 1

₹ 32,485.00

In Stock

Quantity

1

Base Price: ₹ 32,485.00

GST (18%): ₹ 5,847.30

Total Price: ₹ 38,332.30

Antigen

IL-29

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q8IU54

Gene Symbols

IFNL1

Immunogen

Recombinant Human IL-29 Protein (Met1-Thr200)

Quantity

100μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA

Clone

03

Conjugate

Unconjugated

Gene

IFNL1

Gene Alias

cytokine Zcyto21; Cytokine Zcyto22; FNL1; IFN lambda1; IFNL1; IFNL3; IFN-lambda-1; IFN-lambda-3; IFN-lambda-4; IL28B; IL-28B; IL28C; IL-28C; IL29; IL-29; ILN; interferon lambda 1; interferon lambda 3; Interferon lambda1; interferon lambda-1; Interferon lambda-3; interferon, lambda 1; interferon, lambda 3; interferon, lambda 4; interferon-lambda-1; Interleukin; interleukin 29 (interferon, lambda 1); interleukin-28B; Interleukin-28C; interleukin-29; ZCYTO21; ZCYTO22

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

282618

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human IL-29
  • IFN-lambdas constitute a novel family of interferons that mediate the induction of anti-viral protection in a wide variety of cells
  • There are three members in this family, namely lambda1, lambda2, and lambda3, which are also known as IL-29, IL-28A, and IL-28B, respectively
  • Similar to type I IFNs, IFN-lambdas activate an intracellular signaling to promote gene expression
  • IFN-lambdas mediate their anti-viral protection through a class II cytokine receptor complex composed of two essential receptor proteins, CRF2-12/IFN-lambdaR1, which is unique to IFN-lambdas, and CFR2-4/IL-10R2, which is shared with IL-10, IL-22, and IL-26 receptors
  • The IFN-lambdas, IL-28 and IL-29, have recently been reported to prime dendritic cells to induce proliferation of Foxp3-bearing regulatory T cells
  • DCs that differentiate in response to IFN-lambdas express high levels of class I and II MHC gene products, but low levels of costimulatory molecules
  • Moreover, these cells can specifically induce IL-2-dependent proliferation of CD4+CD25+FOXP3+ T cells with contact-dependent suppressive activity.