PIMA531790

KPNA2 Monoclonal Antibody (1E8B7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA531790-Each-of-1 In Stock ₹ 49,350.50

PIMA531790 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

KPNA2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P52292, P52293

Gene Symbols

KPNA2

Immunogen

Purified recombinant fragment of human KPNA2 (AA: 1-530) expressed in E. coli.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

1E8B7

Conjugate

Unconjugated

Gene

KPNA2

Gene Alias

2410044B12Rik; IMA2; importin; importin alpha 2; importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; IPOA 1; IPOA1; IPOA1 QIP2; karyopherin (importin) alpha 2; Karyopherin A2; karyopherin alpha 2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); karyopherin subunit alpha 2; karyopherin subunit alpha-2; Kpna2; m-importin-alpha-P1; nuclear import protein; pendulin; Pore targeting complex 58 kDa subunit; PTAC58; QIP2; RAG cohort 1; RAG cohort protein 1; RCH 1; RCH1; SRP 1; SRP1; SRP1 alpha; SRP1alpha; SRP1-alpha

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

16647, 3838

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-31790 has been tested in indirect ELISA
  • The import of proteins into the nucleus is a process that involves at least 2 steps
  • The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex
  • Imported proteins require a nuclear localization sequence which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart
  • Proteins involved in the first step of nuclear import have been identified in different systems
  • These include the Xenopus protein importin and its yeast homolog, SRP1, which bind to the NLS
  • KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins
  • KPNA2 also may play a role in VJ recombination.