PIPA578034

KPNB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578034-Each-of-1 In Stock ₹ 52,332.00

PIPA578034 - Each of 1

₹ 52,332.00

In Stock

Quantity

1

Base Price: ₹ 52,332.00

GST (18%): ₹ 9,419.76

Total Price: ₹ 61,751.76

Antigen

KPNB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KPNB1

Gene Alias

AA409963; HGNC:6400; IMB1; Impnb; importin 1; importin 90; importin beta; importin beta-1 subunit; importin subunit beta-1; Importin-90; IPO1; IPOB; KapB1; karyopherin (importin) beta 1; karyopherin beta 1; karyopherin subunit beta 1; karyopherin subunit beta-1; karyopherin,beta 1; Kpnb1; MGC2155; MGC2156; MGC2157; NTF97; Nuclear factor p97; pore targeting complex 97 kDa subunit; PTAC97; SCG

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3837

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.32 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

Q14974

Gene Symbols

KPNB1

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of Human Importin beta 1. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: 293T, A431, HeLa, HepG2 Predicted Reactivity: Mouse (99%), Rat (98%), Zebrafish (93%), Xenopus laevis (91%), Chimpanzee (100%), Bovine (100%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope
  • The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins
  • Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex
  • In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate
  • Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore
  • Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex
  • The protein encoded by this gene is a member of the importin beta family.