YAP1 Recombinant Rabbit Monoclonal Antibody (SU33-06), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532117-Each-of-1 | In Stock | ₹ 53,088.50 |
PIMA532117 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,088.50
GST (18%): ₹ 9,555.93
Total Price: ₹ 62,644.43
Antigen
YAP1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P46937
Gene Symbols
YAP1
Immunogen
Synthetic peptide within Human YAP1 aa 421-470
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
SU33-06
Conjugate
Unconjugated
Gene
YAP1
Gene Alias
65 kDa Yes-associated protein, AI325207, cb194, CH211-181P1.5-001, COB1, Protein yorkie homolog, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, transcriptional coactivator YAP1, wu:fc18c04, yap, Yap1, YAP2, Yap65, Yes associated protein 1, Yes1 associated transcriptional regulator, yes-associated protein 1, yes-associated protein 2, yes-associated protein YAP65 homolog, yes-associated protein, 65 kDa, Yki, Yorkie, yorkie homolog, zgc:158380, zYAP
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10413
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene
- Its gene is transcriptionally activated in squamous cell carcinoma cells
- YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway
- The Hippo signaling pathway plays a pivotal role in organ size control and tumour suppression by restricting proliferation and promoting apoptosis
- Also plays key roles in tissue tension, 3D tissue shape, cell proliferation, cell death, and cell migration
- Mutations in the IRF5 gene results in coloboma.