TACC3 Recombinant Rabbit Monoclonal Antibody (SN73-05), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532286-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532286 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
TACC3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q9JJ11, Q9Y6A5
Gene Symbols
TACC3
Immunogen
Synthetic peptide within Human TACC3 aa 35-84
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SN73-05
Conjugate
Unconjugated
Gene
TACC3
Gene Alias
Aint, Arnt interacting protein, ARNT-interacting protein, C86661, ERIC1, ERIC-1, Tacc3, transforming acidic coiled coil 3, transforming acidic coiled-coil containing protein 3, transforming acidic coiled-coil-containing protein 3, transforming, acidic coiled-coil containing protein 3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10460, 21335, 360962
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples
- The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors
- TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10
- Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation
- Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC
- It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.