IFITM3 Recombinant Rabbit Monoclonal Antibody (JU73-02), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532798-Each-of-1 | In Stock | ₹ 46,947.50 |
PIMA532798 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,947.50
GST (18%): ₹ 8,450.55
Total Price: ₹ 55,398.05
Antigen
IFITM3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q01628
Gene Symbols
IFITM3
Immunogen
Synthetic peptide within Human Fragilis aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JU73-02
Conjugate
Unconjugated
Gene
IFITM3
Gene Alias
1110004C05Rik, 1-8U, Cd225, Cdw217, Dispanin subfamily A member 2b, DSPA2b, Fgls, Fragilis, Fragilis 3, Fragilis protein, Ifitm3, ifitm-like protein 1, interferon induced transmembrane protein 3, interferon-induced transmembrane protein 3, interferon-inducible protein 15, Interferon-inducible protein 1-8U, interferon-inducible protein variant 10, IP15, mil-1, Mouse ifitm-like protein 1, rat8
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10410
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins
- IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions
- IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes
- Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons
- In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis
- Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma
- IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.