SMC1 Recombinant Rabbit Monoclonal Antibody (SN20-27), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532341-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532341 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
SMC1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q14683, Q8NDV3, Q920F6, Q9CU62, Q9Z1M9
Gene Symbols
SMC1A, SMC1B
Immunogen
Synthetic peptide within Human SMC1A aa 1,184-1,233
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SN20-27
Conjugate
Unconjugated
Gene
SMC1A
Gene Alias
14S cohesin SMC1 subunit, 5830426I24Rik, CDLS2, chromosome segregation protein SmcB, DKFZp686L19178, DXhXs423e, DXS423E, KIAA0178, MGC138332, mitosis-specific chromosome segregation protein like protein beta, mKIAA0178, RP6-29D12.1, Sb1.8, segregation of mitotic chromosomes 1, segregation of mitotic chromosomes b, segregation of mitotic chromosomes-like 1, SM1A, SMC, SMC (segregation of mitotic chromosomes 1)-like 1, SMC protein, SMC protein 1A, SMC protein 1B, SMC1, SMC1 (structural maintenance of chromosomes 1, yeast)-like 1, SMC1 protein, SMC1 protein cohesin subunit, SMC1 structural maintenance of chromosomes 1-like 1, SMC1 structural maintenance of chromosomes 1-like 2, Smc1a, SMC-1A, smc1a.L, smc1aa, Smc1alpha, SMC-1-alpha, SMC1alpha protein, Smc1b, SMC-1B, SMC1BETA, SMC-1-beta, SMC1L1, Smc1l2, Smcb, SMC-like 1, SMC-protein, structural maintenace of chromosomes 1B, structural maintenance of chromosomes 1, structural maintenance of chromosomes 1 like 1, structural maintenance of chromosomes 1A, structural maintenance of chromosomes 1A a, structural maintenance of chromosomes 1A L homeolog, structural maintenance of chromosomes 1B, structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 1B, Unknown (protein for IMAGE:8058685), XELAEV_18000030mg, xsmc1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
140557, 24061, 27127, 300121, 63996, 8243
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression
- The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects
- This suggests a critical function of SMC family proteins in mitotic chromosome dynamics
- SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells
- Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase
- Mutations in the gene can lead to Cornelia de Lange syndrome 2.