Phospho-MEK1 (Ser298) Recombinant Rabbit Monoclonal Antibody (SD206-7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532367-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532367 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Phospho-MEK1 (Ser298)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P31938, Q01986, Q02750
Gene Symbols
Map2k1
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser298 of Human MEK1aa 271-320
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SD206-7
Conjugate
Unconjugated
Gene
Map2k1
Gene Alias
CFC3, dual specificity mitogen activated protein kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, kinase MEK1, MAP kinase kinase 1, MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2), MAP kinase/Erk kinase 1, Map2k1, map2k1.L, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEK2, mek-2, MEKK1, mitogen activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1 L homeolog, MKK (Thr292), MKK (Thr386), MKK1, MKK2, MP2K1, Prkmk1, PRKMK2, protein kinase, mitogen activated, kinase 1, p45, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1), XELAEV_18018447mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
170851, 26395, 5604
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation
- MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx
- Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1
- It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines
- Mutations in the gene can lead to cardiofaciocutaneous syndrome.