JNK1/JNK3 Recombinant Rabbit Monoclonal Antibody (JJ08-86), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532453-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
JNK1/JNK3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P45983, P49185, P49187, P53779, Q61831, Q91Y86
Gene Symbols
Mapk10, MAPK8
Immunogen
Recombinant protein within Human JNK1 + JNK3 aa 1-423
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
JJ08-86
Conjugate
Unconjugated
Gene
MAPK8
Gene Alias
AI849689, C230008H04Rik, c-Jun N-terminal kinase 1, c-Jun N-terminal kinase 3, JNK, Jnk1, JNK1 beta1 protein kinase, JNK1A2, JNK21B1/2, JNK3, JNK3 alpha protein kinase, JNK3 beta1 protein kinase, JNK3 beta2 protein kinase, JNK3A, JNK3B1, JNK3B2, JNK-46, JUN N-terminal kinase, MAP kinase 10, MAP kinase 8, MAP kinase p49 3F12, MAPK 10, MAPK 8, MAPK10, Mapk8, mitogen activated protein kinase 10, mitogen activated protein kinase 8, mitogen-activated protein kinase 10, Mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, p493F12, p54 gamma, p54-beta, p54bSAPK, PRKM10, Prkm8, protein kinase mitogen-activated 8, SAPb, SAPK gamma, SAPK(beta), SAPK/Erk/kinase 2, SAPK1, SAPK1b, SAPK1c, SAPK-beta, SAPKC, Serk2, stress activated protein kinase beta, stress-activated protein kinase 1, stress-activated protein kinase 1b, Stress-activated protein kinase 1c, stress-activated protein kinase JNK1, Stress-activa
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
116554, 25272, 26414, 26419, 5599, 5602
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The protein encoded by this gene is a member of the MAP kinase family
- MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
- This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli
- The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis
- This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrome c-mediated cell death pathway
- Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation
- Several alternatively spliced transcript variants encoding distinct isoforms have been reported.