JNK3 Recombinant Rabbit Monoclonal Antibody (SD082-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532387-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532387 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
JNK3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P49187, P53779, Q61831
Gene Symbols
MAPK10
Immunogen
Synthetic peptide within Human JNK3 aa 401-450
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone
SD082-09
Conjugate
Unconjugated
Gene
MAPK10
Gene Alias
C230008H04Rik, c-Jun N-terminal kinase 3, hypothetical protein LOC569698, jnk3, JNK3 alpha protein kinase, JNK3 beta1 protein kinase, JNK3 beta2 protein kinase, JNK3A, JNK3B1, JNK3B2, MAP kinase 10, MAP kinase p49 3F12, MAPK 10, MAPK10, mitogen activated protein kinase 10, mitogen-activated protein kinase 10, OTTHUMP00000161181, OTTHUMP00000161183, OTTHUMP00000218718, p493F12, p54-beta, p54bSAPK, PRKM10, SAPb, SAPK(beta), SAPK/Erk/kinase 2, SAPK1B, SAPK-beta, SAPKC, Serk2, Stress activated protein kinase beta, stress-activated protein kinase 1b, Stress-activated protein kinase JNK3, zgc:123234
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
25272, 26414, 5602
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- MAPK10 (JNK3) is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
- MAPK10 is involved in neuronal apoptosis and phosphorylates MAP2K4
- MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development
- This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs)
- Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis
- Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (NhpK4)
- Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis
- Four alternatively spliced transcript variants encoding distinct isoforms have been reported.