PIMA532416

Phospho-Cdc6 (Ser54) Recombinant Rabbit Monoclonal Antibody (SD08-47), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532416-Each-of-1 In Stock ₹ 47,481.50

PIMA532416 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Phospho-Cdc6 (Ser54)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q99741

Gene Symbols

CDC6

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 aa 41-90

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot, Western Blot

Clone

SD08-47

Conjugate

Unconjugated

Gene

CDC6

Gene Alias

CDC18(S.pombe), CDC18L, cdc18-related protein, CDC6, CDC6 cell division cycle 6 homolog, CDC6-related protein, Cell division control protein 6 homolog, cell division cycle 6, cell division cycle 6 homolog, HsCDC18, HsCDC6, p62(cdc6)

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

990

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication
  • This protein functions as a regulator at the early steps of DNA replication
  • It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase
  • The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks
  • Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.