CDK6 Recombinant Rabbit Monoclonal Antibody (SD20-50), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532357-Each-of-1 | In Stock | ₹ 54,557.00 |
PIMA532357 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 54,557.00
GST (18%): ₹ 9,820.26
Total Price: ₹ 64,377.26
Antigen
CDK6
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q00534
Gene Symbols
CDK6
Immunogen
Synthetic peptide within Human Cdk6 aa 277-326
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SD20-50
Conjugate
Unconjugated
Gene
CDK6
Gene Alias
5830411I20, AI504062, CDK6, CDKN6, Cell division protein kinase 6, CR2 protein kinase, Crk2, cyclin dependent kinase 6, cyclin-dependent kinase 6, MCPH12, MGC59692, PLSTIRE, Serine/threonine-protein kinase PLSTIRE
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1021
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CDK6 functions as a cell-cycle initiator protein
- This protein is coexpressed and copurified with CyclinD1
- They are critical regulators of cell cycle progression
- The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression
- CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles
- Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).