Perilipin 1 Recombinant Rabbit Monoclonal Antibody (JM10-96), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532597-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532597 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Perilipin 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O60240, Q8CGN5
Gene Symbols
Plin1
Immunogen
Synthetic peptide within Human Perilipin A aa 470-510
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
JM10-96
Conjugate
Unconjugated
Gene
Plin1
Gene Alias
6030432J05Rik, adipocyte lipid droplet binding protein, FPLD4, Lipid droplet-associated protein, PERI, PERIA, perilipin, perilipin 1, perilipin A, perilipin B, perilipin-1, PLIN, PLIN1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
103968, 5346
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Adipose tissue is an energy reserve in animals and is strictly regulated in nondomestic species
- Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin, adipocyte complement related protein of 30 kDa (Acrp30), resistin, and perilipin
- Perilipin is an intracellular neutral lipid droplet protein that is hormonally regulated
- This protein is localized exclusively to the surface of lipid droplets
- In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A
- Once activated, perilipin has inhibitory affects upon hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body
- Perilipin expression is limited to adipocytes and steroidogenic cells
- There are currently two known isoforms, Perilipin A and B
- Both of these proteins are encoded by a single-copy gene and are the result of differential splicing events.