FKBP12 Recombinant Rabbit Monoclonal Antibody (JM11-09), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532611-Each-of-1 | In Stock | ₹ 46,413.50 |
PIMA532611 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
FKBP12
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P26883, P62942, Q62658
Gene Symbols
FKBP1A
Immunogen
Synthetic peptide within Human FKBP12 aa 76-108
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
JM11-09
Conjugate
Unconjugated
Gene
FKBP1A
Gene Alias
12 kDa FK506-binding protein, 12 kDa FKBP, calstabin 1, calstabin-1, EC 5.2.1.8, FK506 binding protein 1a, FK506 binding protein 1A, 12kDa, FK506 binding protein 2 (13 kDa), FK506 binding protein12, FK506-binding protein 1, FK506-binding protein 1 (12kD), FK506-binding protein 12, FK506-binding protein 1a, FK506-binding protein 1A (12kD), FK506-binding protein, T-cell, 12-kD, Fkbp, FKBP1, FKBP12, FKBP-12, FKBP12-Exip3, Fkbp1a, FKBP-1A, Fkbp2, Immunophilin FKBP12, peptidyl-prolyl cis-trans isomerase FKBP1A, PKC12, PKCI2, PPIASE, PPIase FKBP1A, protein kinase C inhibitor 2, rotamase
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14225, 2280, 25639
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking
- The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin
- It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor
- It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor
- In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.