PABPN1 Recombinant Rabbit Monoclonal Antibody (JM11-28), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532621-Each-of-1 | In Stock | ₹ 48,104.50 |
PIMA532621 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,104.50
GST (18%): ₹ 8,658.81
Total Price: ₹ 56,763.31
Antigen
PABPN1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q86U42, Q8CCS6
Gene Symbols
PABPN1
Immunogen
Synthetic peptide within Human PABPN1 aa 4-51
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot
Clone
JM11-28
Conjugate
Unconjugated
Gene
PABPN1
Gene Alias
mPABII, Nuclear poly(A)-binding protein 1, OPMD, PAB2, PABII, PABP2, PABP-2, Pabp3, PABPN1, poly(A) binding protein 2, poly(A) binding protein II, poly(A) binding protein nuclear 1, poly(A) binding protein, nuclear 1, poly(A)-binding protein 2, poly(A)-binding protein II, polyA binding protein II, polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
54196, 8106
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
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Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails
- The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt
- At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm
- This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease
- Related pseudogenes have been identified on chromosomes 19 and X
- Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.