NDRG1 Recombinant Rabbit Monoclonal Antibody (JM32-02), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532730-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532730 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
NDRG1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q62433, Q6JE36, Q92597
Gene Symbols
NDRG1
Immunogen
Synthetic peptide within Human NDRG1 aa 345-394
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot
Clone
JM32-02
Conjugate
Unconjugated
Gene
NDRG1
Gene Alias
CAP43, CMT4D, differentiation-related gene 1 protein, DRG1, DRG-1, GC4, HMSNL, Ndr1, Ndrg1, Ndrl, nickel-specific induction protein Cap43, NMSL, N-myc downstream regulated 1, N-myc downstream regulated gene 1, N-myc downstream-regulated gene 1 protein, Protein Ndr1, protein NDRG1, protein regulated by oxygen-1, PROXY1, Reducing agents and tunicamycin-responsive protein, Rit42, RTP, TARG1, TDD5
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
10397, 17988, 299923
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- NDRG1 is a 394 amino acid cytoplasmic protein belonging to the NDRG family
- It interacts with APO A-I and A-II and plays a role in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth and differentiation
- Its defect causes Charcot-Marie-Tooth disease type 4D (CMT4D) that is characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations on nerve biopsy, slowly progressive distal muscle atrophy and weakness, absent deep tendon reflexes and hollow feet
- NDRG1 plays a growth inhibitory role and serves as a marker of differentiation
- It is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon and the cells that border the lumen.